Occult HBV infection among a cohort of Nigerian adults

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Occult HBV infection among a cohort of Nigerian adults.

OBJECTIVE To determine markers of HBV infection and detect the presence of its occult infection in serum of a cohort of adult Nigerians. METHODOLOGY The study involved 28 adult Nigerians with viral hepatitis (Group 1) and 28 apparently healthy adult Nigerians as controls (Group 2). Their sera were assayed for HBsAg, HBeAg, anti-HBe, anti-HBc, anti-HBs, and anti-HCV, while HBV DNA was determin...

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The clinical significance of occult HBV infection

The presence of hepatitis B virus (HBV) DNA in HBV surface antigen (HBsAg)-negative individuals is defined as occult HBV infection (OBI). OBI is related in some cases to infection with variant viruses (S-escape mutants) undetectable by HBsAg commercial kits. More frequently, however, it is due to infection with wild-type viruses that are strongly suppressed in their replication activity. OBI ma...

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The prevalence of occult hepatitis B virus (hbv) infection in a large multi-ethnic haemodialysis cohort

BACKGROUND Haemodialysis patients are at increased risk of exposure to blood borne viruses. To reduce transmission in the UK, all haemodialysis patients are regularly screened, and if susceptible to Hepatitis B virus (HBV) infection, vaccinated. METHODS This retrospective study was undertaken to determine the HBV immune status in a large dialysis cohort and the prevalence of occult HBV infect...

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Occult HBV Infection: A Faceless Enemy in Liver Cancer Development

The hepatitis B virus (HBV) represents a worldwide public health problem; the virus is present in one third of the global population. However, this rate may in fact be higher due to occult hepatitis B virus infection (OBI). This condition is characterized by the presence of the viral genome in the liver of individuals sero-negative for the virus surface antigen (HBsAg). The causes of the absenc...

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ژورنال

عنوان ژورنال: The Journal of Infection in Developing Countries

سال: 2009

ISSN: 1972-2680

DOI: 10.3855/jidc.415